Publications
2025
Verena Rukes, Chan Cao*, Advancing nanopore technology towards protein identification and sequencing, Trends in Biochemical Sciences, 2025 ()
Juan F. Bada Juarez‡, Nuria Cirauqui‡, Fernando Augusto T. P. Meireles, Louis W. Perrin, Julian Barry, Monika Bokori-Brown, Maria J. Marcaida, Chan Cao*, Matteo Dal Peraro*, Exploring new nanopore sensors from the aerolysin family, Small, 2025 (in print)
Jiaxuan Li, Chenguang Yang, Ruihan Dong, Juan F. Bada Juarez, Lei Wang, Maximilian E. Wettstein, Dali Wang, Chan Cao, Ying Lu, Chen Song, Mechanism-driven screening of membrane-targeting and pore-forming antimicrobial peptides, bioRxiv ()
Marwan El Chazli, Juan F. Bada Juarez, Louis W. Perrin, Jiajie Gao, Chan Cao*, Enhanced Analytes Capture by Engineering Electrostatics at the Entry of Aerolysin Nanopore, Helvetica Chimica Acta, 2025, e202400180 ()
Axel Camazzola, Elena Buglakova, Louis W. Perrin, Verena Rukes, Chan Cao*, Eliminating the Interference of Neighboring Nucleobases in Aerolysin for Nanopore Sequencing, ACS. Sens. 2025, XXXX, XXX, XXX-XXX ()
Yun Zhang, Chan Cao*, Aerolysin nanopores for single-molecule analysis, CHIMIA, 2025, 79, 18 ()
Jana S. Anton, Ioan Iacovache, Juan F. Bada Juarez, Luciano A. Abriata, Louis W. Perrin, Chan Cao, Maria J. Marcaida, Benoît Zuber*, Matteo Dal Peraro*, Aerolysin Nanopore Structures Revealed at High Resolution in a Lipid Environment, J. Am. Chem. Soc. 2025, 147, 6, 4984-4992 ()
2024
Tereza Roesel#, Chan Cao#, Juan F. Bada Juarez, Matteo Dal Peraro*, Sylvie Roke*, "Dissecting the Membrane Association Mechanism of Aerolysin Pores at Femtomolar Concentrations Using Water as a Probe", Nano Lett. 2024, 24, 44, 13888–13894 ()
Verena Rukes, Mathieu E. Rebeaud, Louis W. Perrin, Paolo De Los Rios*, Chan Cao*, Single-molecule evidence of Entropic Pulling by Hsp70 chaperones, Nat Commun 2024, 15, 8604 ()
Research highlight: The secret strength of our cell guards (link)
Samuel Rommelaere, Alexia Carboni, Juan F. Bada Juarez, Jean-Philippe Boquete, Luciano A. Abriata, Fernando Teixeira, Pinto Meireles, Verena Rukes, Crystal Vicent, Shu Kondo, Marc S. Dionne, Matteo Dal Peraro, Chan Cao, Bruno Lemaitre*, A humoral stress response protects drosophila tissues from antimicrobial peptides, Current Biology, 2024, 34, 7, 1426 - 1437.e6
Chan Cao*, Pedro Magalhães, Lucien F. Krapp, Juan F. Bada Juarez, Simon Finn Mayer, Verena Rukes, Anass Chiki, Hilal A. Lashuel*, Matteo Dal Peraro*, Deep Learning-Assisted Single Molecule Detection of Protein Post-Translational Modifications with a Biological Nanopore, ACS Nano 2024, 18, 2, 1504–1515 ()
Research highlight: Towards early diagnosis of neurodegenerative diseases with nanopore detection and AI (link), Nanopore and deep learning changeb disease diagnostics ()